There is no single success rate for Gamma Knife, because outcomes vary considerably according to the disease being treated.
For tumors, success is commonly evaluated through local tumor control or prevention of further growth, rather than simply complete disappearance.
For AVMs, the treatment effect develops gradually as abnormal vessels close.
For trigeminal neuralgia, the primary outcome is reduction or elimination of facial pain. Mayo Clinic notes that Gamma Knife is successful at stopping pain for most people, although pain can return in some patients, often within several years.